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Home > FAQs > Can labs tell between synthetic and real urine

Can labs detect synthetic urine in 2025?

Can labs tell the difference between real and synthetic urine?

The short answer is no, when the synthetic pee is made correctly labs won't detect it during a test. You might be wondering how can we be sure of this? Well, Cansford Labs even wrote an article on this very subject, where they discuss how difficult it is to detect synthetic urine. In the article they even show that it is better to try to catch the person being tested substituting the sample.

However, not all synthetic urines are the same quality and some are detectable when labs test for fake urine, as we discuss in the following video.

Can synthetic pee be detected in a lab?

Given the right synthetic urine, as discussed in the video below, labs won't be able to detect it, so make sure you use a proven synthetic urine.



Video transcript:

[The video shows a syringe of water next to a vial of Dr John's Famous Pee Pee synthetic urine]. This is innovative research technology, the makers of the Urinator and Dr John’s famous Pee pee. We have some frequently asked questions that people have asked over the last 27 years, we’ve been in business since 1998, and we’re going to try to answer them pretty quick.

Can a lab tell the difference between real and synthetic urine?

The answer is if the synthetic urine was made correctly, they will not be able to determine it. However, keep in mind that not all synthetics are the same.

Innovative research’s Dr John’s Famous Pee Pee is a concentrated liquid and it is basically self-preserving. There are no outside chemicals, foreign chemicals that are brought in to stabilise it, that’s why it’s in concentrated form.

Most all synthetics I’ve seen on the market are either powdered or premixed. Of it’s a premixed urine, the problem you have with premixed urine, is that bacteria growth can start growing. So what a lot of companies have had to do is they have started having to add some type of preservative, some type of anti-bacterial component to that urine so it will pass. The problem is that when you start adding foreign substances to something that should be all natural if the lab decides to look for that specific thing and they find it, they’re going to know that it’s synthetic.

So Dr John’s you don’t have to worry about everything in its natural that’s found in it is found in the human body.
When it comes to pre mixes, I would be afraid of them. If labs decide to start testing, and I’m not sure if they have or not, but if they decide to start testing for outside components there has to be something there to stabilise the bacteria in the samples.

Other Synthetic urine FAQs
 
1 https://blog.cansfordlabs.co.uk/synthetic-urine-lab-perspective reference discusses how synthetic urine is made and difficulties in detecting mean that it is best to catch someone substituting.

2. Catching Fakes: New Markers of Urine Sample Validity and Invalidity  published in the Journal of Analytical Toxicology in 2017. The authors are Melissa M. Goggin, Cheng-Min Tann, Anna Miller, An Nguyen and Gregory C. Janis




Last update: 04.12.2025